منابع مشابه
Generation of nonidentical compartments in vesicular transport systems
How can organelles communicate by bidirectional vesicle transport and yet maintain different protein compositions? We show by mathematical modeling that a minimal system, in which the basic variables are cytosolic coats for vesicle budding and membrane-bound soluble N-ethyl-maleimide-sensitive factor attachment protein receptors (SNAREs) for vesicle fusion, is sufficient to generate stable, non...
متن کاملVesicular Trans-Cell Wall Transport in Fungi: A Mechanism for the Delivery of Virulence-Associated Macromolecules?
Fungal cells are encaged in rigid, complex cell walls. Until recently, there was remarkably little information regarding the trans-fungal cell wall transfer of intracellular macromolecules to the extracellular space. Recently, several studies have begun to elucidate the mechanisms that fungal cells utilize to secrete a wide variety of macromolecules through the cell wall. The combined use of tr...
متن کاملThe Zinc Transport Systems and Their Regulation in Pathogenic Fungi
Zinc is an essential micronutrient required for many enzymes that play essential roles in a cell. It was estimated that approximately 3% of the total cellular proteins are required for zinc for their functions. Zinc has long been considered as one of the key players in host-pathogen interactions. The host sequesters intracellular zinc by utilizing multiple cellular zinc importers and exporters ...
متن کاملVesicular Transport: EnSNAREd by GAPs
How are SNARE proteins included into transport vesicles? One way is through the interaction with ArfGAP proteins. A recent study reports that the ArfGAP Hrb can wrap around the SNARE VAMP7, causing its endocytosis by clathrin-coated vesicles.
متن کاملVesicular transport earns a Nobel.
The field of intracellular traffic is celebrating the awarding of the 2013 Nobel Prize in Physiology or Medicine to three of its most distinguished scientists--James Rothman, Randy Schekman, and Thomas Südhof--for their discoveries on the molecular mechanisms of vesicular transport. Their outstanding achievements serve as inspiration for the next generation of scientists to continue the task of...
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ژورنال
عنوان ژورنال: Future Microbiology
سال: 2011
ISSN: 1746-0913,1746-0921
DOI: 10.2217/fmb.11.112